Abstract Background Resistance of cholangiocarcinoma to chemotherapy is a major problem in cancer treatment. The mechanism of resistance is believed to involve phosphoinositide-3- kinase (PI3K)/Akt activation. Although the platinum-containing compound oxaliplatin has been extensively used in the treatment of several solid tumors. recent data regarding its use to treat cholangiocarcino... https://www.diegojavierfares.com/amazing-find-Bonnet-Protector-Guard-Suits-Holden-Calais-VT-VX-8-1997-9-2002-H260B-hot-choice/