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Targeting the NLRP3 inflammasome abrogates cardiotoxicity of immune checkpoint blockers

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Background Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of many malignant tumors. However. ICI-induced hyper-immune activation causes cardiotoxicity. Traditional treatments such as glucocorticoids and immunosuppressants have limited effectiveness and may even accelerate tumor growth. https://www.diegojavierfares.com/limited-save-1-64-Lowndes-2010-Triple-Eight-Race-Engineering-Suits-Holden-VE-Commodore-64168-special-save/
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